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At the International Symposium on Clinical Neuroscience, Dr. Popper, a child and adolescent Psychiatrist and Psychopharmacologist from McLean Hospital and Harvard Medical School, presents information specific to single micronutrient and broad spectrum micronutrient approaches for treating mood disorders. He also discusses several relevant mechanisms by which nutrients could have the effects that have been measured, and some guidelines for healthcare practitioners in applying the micronutrient treatment in their practices.