Nutrient-medication interactions are often the biggest obstacles facing those who want to improve their mental health using Daily Essential Nutrients. 

We have some wonderful news: academic scientists in New Zealand who are trained in biochemistry and pharmacology would like to evaluate the mechanisms that could explain the types of nutrient-psychiatric medication interactions we have observed.

As their first study, the scientists propose to evaluate pharmacokinetic interactions involving cytochrome p450 (CYP) enzymes. Twelve normal, healthy volunteers will have their CYP enzyme activity evaluated, then take Daily Essential Nutrients for a few weeks and have their CYP enzyme activity evaluated a second time.

Future studies will hopefully evaluate pharmacodynamic mechanisms, including in people taking psychiatric medications.

Dr. Bonnie Kaplan at the University of Calgary is trying to assemble a group of potential donors to further this line of research. As you can imagine, funding agencies are not interested (so far) in supporting basic studies in normal healthy people! 

The studies are not very expensive compared to clinical trials: the first one will cost <$30,000 USD. Bonnie manages two donor-advised Nutrition and Mental Health research funds (one in the United States and one in Canada) that could be used for donations so that your support will result in a charitable tax receipt. The New Zealand research can be supported from both funds.

Bonnie has suggested that some donors may have expertise or clinical experience, and they could serve as resources to look at potential studies…..a sort of scientific advisory committee.

If you are willing to donate toward this effort, and/or if you would like to be kept informed about the research ideas and progress, please email Bonnie: kaplan@ucalgary.ca.

If you have any questions, feel free to email us or Bonnie directly. 

Best regards,

- The Hardy Nutritionals Science Team

About Hardy Nutritionals®

Hardy Nutritionals® multivitamin-mineral products are powered by our proprietary NutraTek™ mineral delivery technology, which combines each mineral with specialized organic molecules—just like nature—to optimize absorption and distribution to body cells. Our flagship supplement, Daily Essential Nutrients, is widely considered to be the most research-backed micronutrient treatment.