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Micronutrient formulation greatly improves brain function in rats.

Researchers at the world-renowned Canadian Centre for Behavioural Neuroscience conducted a series of controlled studies with rats fed a micronutrient formulation co-developed by Hardy Nutritionals® founder David Hardy to test its effects on brain injuries and brain-related disorders. Neuroscientists performed surgery on a group of young rats, removing either the entire frontal lobe of the brain or part of the parietal lobe. The researchers then fed one group of these rats Purina Rat Chow (considered to be an ideally fortified lab rat diet with 22 added vitamins and minerals) and another group the same base diet fortified with the more complete, specially-processed micronutrient formulation. Brain recovery was significantly enhanced in the micronutrient-fed rats. As the rats recovered, researchers observed that the micronutrient-fed rats showed significantly calmer behavior and dramatically improved cognitive function compared with Purina-fed rats. The brain cells of micronutrient rats were also more complexly-branched and better connected with neighboring cells than the brain cells of Purina-fed rats. The calmer behavior and enhanced cognitive function of micronutrient-treated rats are consistent with results documented by researchers around the world in many people with mood, anxiety, and behavioral disorders. The enhanced brain cell connectivity observed by researchers supports the use of micronutrient formulations for human brain recovery in conjunction with brain rehabilitation therapies.

Factors influencing frontal cortex development and recovery from early frontal injury.

Halliwell C, Comeau W, Gibb R, Frost DO, Kolb B. Developmental Neurorehabilitation. 2009;12(5):269-78.

Micronutrient Treatment of Emotional Dyscontrol Following Traumatic Brain Injury

Emotional dyscontrol following traumatic brain injury (TBI) impairs social relationships and employability. Micronutrients (minerals, vitamins) stabilize emotional lability in psychiatric patients, and various individual nutrients have been used to treat experimental brain injury in laboratory animals in the acute phase. However, the current case report appears to be the first documentation of micronutrients resulting in normalization of emotion regulation in a long-standing brain injury in a human.

Case presentation: A broad-spectrum formula of micronutrients was evaluated in a 35-year-old male who had incurred a severe TBI eight years previously. Resolution of most post-TBI symptoms was achieved during those eight years, but not his episodic loss of emotional control, which psychiatrists evaluated as being permanent. The trial of micronutrients began after five weeks of baseline symptom monitoring with a mood stability scale. By three months mood stability had improved markedly according to data submitted by two raters (the patient and his clinician) who were blind to each other’s evaluations. Data collection continued for one year, showing significant improvement (p<.0001), at which time the patient reported that his emotional control had returned to his pre-TBI level. The improvements led to his establishing his own business and improving his family relationships.

Micronutrient treatment resulted in resolution of this patient’s longstanding post-TBI emotional dyscontrol. Broad-spectrum micronutrient formulas are showing benefit for the treatment of mood lability in various types of psychiatric patients; this report indicates there is also potential value in using them for the emotional dyscontrol found in post-TBI patients.

Micronutrient Treatment of Emotional Dyscontrol Following Traumatic Brain Injury

Kaplan, B. J., Leaney, C., Tsatsko, E. Annals of Psychiatry and Mental Health. 29 August 2016.